Epidemiology and Biostatistics

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Lok R. Pokhrel

Lok Pokhrel portrait

Assistant Professor of Instruction

Contact

928 Ritter Annex
1301 Cecil B. Moore Ave.
Philadelphia, PA 19122
Office: 215-204-9110
Fax: 215-204-1854
Lok.pokhrel@temple.edu

Education

  • Post-doc Nanotoxicology, National Research Council of National Academies/US Environmental Protection Agency, Corvallis, OR
  • PhD, Environmental Health, East Tennessee State University
  • MS, Biological Sciences, East Tennessee State University
  • MS, Zoology, Degree Campus, Tribhuvan University, Nepal
  • BS, Zoology, Mechi Multiple College, Tribhuvan University, Nepal

Biography

Lok R. Pokhrel is an Assistant Professor of environmental health in the College of Public Health’s Department of Epidemiology and Biostatistics at Temple University. He also leads Pokhrel's Nanotechnology Health Lab (PNHL). Trained as a toxicologist and risk assessor, for the last several years Dr. Pokhrel’s work has focused on understanding how both the legacy and emerging contaminants impact human health and the environment. His current research seeks to understand the potential human health risk from exposure to engineered nanomaterials (ENMs) that are flooding our marketplace. To this end, research is conducted at the intersection of three spheres: nanomaterial surface chemistry, environmental variables, and biological systems. From identifying the roles of physicochemical attributes of ENMs can play on nanotoxicity to the development of structure-activity relationship (SAR) models, from understanding the roles of natural water chemistry in modulating ENM toxicity to the development of biouptake and risk models, and elucidating mechanistic basis of ENM toxicity via probing changes at nano-bio interfaces using state-of -the-art techniques (e.g., light/electron microscopy, fluorescence microscopy, surface analytical spectroscopies, X-ray diffraction, dynamic light scattering), Pokhrel’s work has made significant impact to this new and evolving field of Nanoscience and Nanotechnology.

Research Interests

  • Engineered Nanomaterials
  • Environmental Health
  • Human Toxicology
  • Water Quality