Temple University

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Mark H. Weir

Mark H. Weir, Ph.D.

Assistant Professor


1301 Cecil B. Moore Avenue
Ritter Annex, 9th floor (004-09)
Philadelphia, PA  19122
Office: 215-204-9160
Fax: 215-204-1854



Dr. Weir in an Environmental Engineer with 9.5 years of consulting and research experience.  He earned his Bachelor's degree in Environmental Engineering from Wilkes University in 2004 and after a short time proceeded to Drexel University to work with Dr. Charles Haas. 

At Drexel Dr. Weir developed his skills in environmental and engineered systems modeling and quantitative microbial risk assessment (QMRA).  In the summer of 2009 he graduate with a Ph.D. In Environmental Engineering and started his postdoctoral work at Michigan State University (MSU) with the Center for Advancing Microbial Risk Assessment (CAMRA).  As Associate Director of CAMRA Dr. Weir helped manage the large center of researchers while procuring his own research funding through EPA for predictive risk and environmental systems modeling research.  While at MSU he also opened a science and engineering consulting firm, CAMRA Consultants LLC.

Before joining Temple Dr. Weir worked as an Environmental Engineer with the Office of Groundwater and Drinking Water, Office of Water at the Environmental Protection Agency (EPA).  While at EPA he worked on the Lead and Copper rule updates, Perchlorate rule, CCL4 and stochastic techniques for recreational water quality.


Book Chapters

Pope, J.M., Weir, M.H., Rose, J.B., “History of Water and Health” in The Evolution of Water Supply Through the Millennia (2012) International Water Association.  ISBN: 9781843395409

Conference Proceedings

Rose, JB., Weir, MH. (2010) Theoretical Modeling Approaches to Investigating the Spread of Disease in Airports and in Aircraft: Characterizing the Risk of Tuberculosis in Commercial Aircraft by Using Quantitative Microbial Risk Assessment. Proceedings of the Research on the Transmission of Disease in Airports and on Aircraft: A Symposium, Washington DC, 17 Sept 2009

Select Journals

Coulliette, A.D., Enger, K.S., Weir, M.H. (2012) “Risk Reduction Assessment of Waterborne Salmonella and Vibrio by a chlorine contact disinfectant Point-of-Use Device International Journal of Hygiene and Environmental Health. http://dx.doi.org/10.1016/j.ijheh.2012.08.007 

Weir, M.H., Razzolini, M.T.P, Masago, Y., Rose, J.B. (2011) “Water Reclamation Redesign For Reducing Cryptosporidium Risks At A Recreational Spray Park Using Stochastic Models.” Water Research 45(19):  6505-6514

Weir, M.H., Haas, C.N. (2011) “Development of the First of a Two Stage Mechanistic Dose Response Model: Effect of Delivered Dose on the Dose Response of Bacillus anthracis” Environmental Science and Technology 45(13):  5828-5833

Teske, S.S., Huang, Y., Weir, M.H., Bartrand, T.A., Tamrakar, S.B., Haas, C.N. (2011) “Animal and Human Dose-Response Models for Brucella Species” Risk Analysis 31(10):  1576-1596

Razzolini, M.T.P, Weir, M.H., Rose J.B., (2011) “Risk of Giardia Infection in a Peri-Urban Area Drinking Water Supply in Sao Paulo, Brazil” International Journal of Environmental Health 21(3): 222-234

Watanabe, T., Bartrand, T.B., Weir, M.H., Haas, C.N. (2010) “Development of a Dose-Response Model for SARS Coronavirus” Risk Analysis 30(7):  1128-1138 

Weir, M.H. and Haas, C.N (2009). “Quantification of the Effects of Age on the Dose Response of Variola major in Suckling Mice.” Human and Ecological Risk Assessment. 15(6): 1245-1256

Huang, Y., Bartrand, T.A., Haas, C.N., Weir, M.H. (2009). “Incorporating Time Post Inoculation into a Dose Response Model of Yersinia pestis in Mice.” Journal of Applied Microbiology. 107(3): 727-735

Bartrand, T.A., Haas C.N., Weir, M.H. (2008). “Dose Response Models for Inhalation of Bacillus anthracis Spores: Interspecies Comparisons.” Risk Analysis. 28(4): 1115-1124

Bartrand, T.A., Weir, M.H., Haas, C.N. (2007). “Advancing the Quality of Drinking Water: Expert Workshop to Formulate a Research Agenda.” Environmental Engineering Science 24(7): 863-872.

Walski, T., Bezts, W., Posluszny, E.T., Weir, M.H., Whitman, B.E. (2006). “Modeling Leakage Reduction Through Pressure Control.” Journal AWWA 98(1): 147-155.

Select Presentations:

Society for Risk Analysis, Annual Meeting, “Stochastic Modeling of Water Reclamation Treatment Systems Addressing Cryptosporidium Risks at a Recreational Spray Park” Charleston SC, December 2011

Society for Risk Analysis, Annual Meeting.  “Virus and Non-Spore Forming Bacteria QMRA of Fomites Accounting for Surface Sampling Efficiencies” Charleston SC, December 2011

Society for Risk Analysis, Annual Meeting, “Use of Quantitative Microbial Risk Assessment and Predictive Modeling to Inform Beach Closures” Charleston SC, December 2011

Association of Environmental Engineering and Science Professors, Bootstrap Uncertainty Analysis of K-Nearest Neighbor Classification for Microbial Source Tracking. Tampa FL, July 2011

International Water Association, “The Exposure Assessment, a Key to the QMRA Framework” Montreal, Canada, September 2010

DHS Science and Technology Directorate, Science and Technology Advisory Committee, ”The Center for Advancing Microbial Risk Assessment” Frederick, Maryland, April 2010

DHS Science and Technology Directorate Office of University Programs, Annual University Summit, “Development of an Estuary Protection Response Strategy Using QMRA” Washington, DC, March 2010

Grants & Contracts

Mark H. Weir (Co-Principal): “Forecasting Beach and Nearshore Health Effects Using QMRA”, Sponsored by the Great Lakes Restoration Initiative, Environmental Protection Agency, $65,000 (September 2010 –September 2012)

Mark H. Weir (Principal): “Development of a Physiologically Based Pathogen Transport and Kinetics Model for Inhalation of Pathogens”, Sponsored by the Department of Homeland Security, Science and Technology Directorate $10,000 (September 2008 –August 2010)


Dr. Weir investigates the connection between environmental exposures to water and health impacts.  He specifically researches how current and future engineering practices and technology can either mitigate or exacerbate the health impacts.  Through investigating both natural and produced water quality a linkage can be found and exploited to further our understanding of where to go with future policy and technology.

Clinical Interests

Research Interests:

  • QMRA – quantitative microbial risk assessment
  • Complex systems modeling and analytics
  • Health effect optimization through environmental and engineering controls
  • Water treatment technology and policy
  • Storm and wastewater management technology and policy